CHED 944 |
| The food and beverage industry is increasingly replacing sugar with artificial sweeteners in a range of products traditionally containing sugar. However, there is ongoing controversy over the supposed health risks of artificial sweeteners. One substance which may be in question is sucralose, a non-caloric sweetener known by the trade name Splenda. It is produced from sucrose in a proprietary process, by which three of sucrose's hydroxyl groups are substituted with chlorine atoms. Splenda is reported by manufacturers as largely excreted by the body and mostly unchanged in its form. However, transformation and absorption regarding the molecule has been reported in vivo. In this study, a coupled enzyme system involving invertase and fructose dehydrogenase will be used to monitor the effects of sugar substrates and investigate the possibility of covalent modification or inhibition of sugar binding enzymes by sucralose. |
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Undergraduate Research Poster Session: Biochemistry
2:00 PM-4:00 PM, Monday, March 26, 2007 Hyatt Regency Chicago -- Riverside Center, Poster
Division of Chemical Education |