Identification of diastereomeric interactions in zeolites by solid state Nuclear Magnetic Resonance (NMR)

CHED 1410

Hien T Huynh, hienhuyn@msmc.la.edu1, Migi Park2, and Deniz Cizmeciyan, dcizmeciyan@msmc.la.edu1. (1) Department of Physical Sciences and Mathematics, Mount St. Mary's College, 12001 Chalon Rd., Los Angeles, CA 90049, (2) Department of Physical Science and Mathematics, Mount St. Mary's College, 12001 Chalon Rd., Los Angeles, CA 90049
Chirals are often found in drugs to treat diseases, where only one of the “mirror images” is the active compound. By obtaining the correct “mirror image” in pure form is expensive; therefore, developing economical methods of producing chirally pure compounds would be efficient. We are investigating the selectivity of various zeolites in adsorption of D, L and DL amino acids. Zeolite adsorbs more than one stereoisomer, which displays a preference for DL over the dimers of DD or LL. If the co-adsorption of D and L stereoisomers is preferred, the removal of a 1:1 ratio of enantiomers from the solution would lead to further enantiomeric enrichment of the remaining solution. The technique of 13C NMR was used throughout our project, to determine the adsorption of alanine and phenylalanine in zeolite NaY. Our cross polarization magic angle spinning data will be shown and differences between species will be discussed.
 

Undergraduate Research Poster Session: Physical Chemistry
2:00 PM-4:00 PM, Monday, March 26, 2007 Hyatt Regency Chicago -- Riverside Center, Poster

Division of Chemical Education

The 233rd ACS National Meeting, Chicago, IL, March 25-29, 2007