CHED 483 |
| Due to its easily tailored surface morphology and high surface area, porous silicon (por-Si) has shown great potential toward a myriad of applications including microscale sensors and biomedical implants. Unfortunately, its native hydride- termination quickly degrades under ambient and aqueous environments. Literature methods report a variety of methods that allow for the preparation of stable organic monolayers on porous silicon through direct, covalent silicon-carbon linkages. Organic monolayers of varying chain length were prepared by microwave, carbocation, thermal, and Lewis acid mediated hydrosilylation. The functionalized por-Si samples, as well as control and oxidized samples, were immersed in simulated gastric fluid and transferred to simulated intestinal fluid to replicate the conditions of potential por-Si biosensors or medicinal delivery systems in the human gastrointestinal track. Degradation of the underlying por-Si surface was monitored using infrared spectroscopy at various time intervals. |
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Undergraduate Research Poster Session: Nanotechnology
11:00 AM-1:00 PM, Monday, March 26, 2007 Hyatt Regency Chicago -- Riverside Center, Poster
Division of Chemical Education |