Award Address (Herbert C. Brown Award for Creative Research in Synthetic Methods, sponsored by Purdue Borane Research Fund and the Herbert C. Brown Award Endowment). Two decades of research on the Diels-Alder reaction

ORGN 231

David A. Evans, Department of Chemistry & Chemical Biology, Harvard University, Cambridge, MA 02138
The Diels-Alder cycloaddition is arguably organic chemistry's most powerful carbon-carbon bond forming reaction and new advances are being continually made to improve the stereochemical attributes of this valuable process. This lecture will highlight the advances that have been made in our laboratory over the last two decades. These advances include the development of both chiral auxiliaries and chiral catalysts. Applications to current target-oriented synthesis projects will be discussed.