Introducing physical analytical chemistry across the curriculum using fluorescence instrumentation and the case study approach: Nut poisoning (or too much of a good thing); fluorescence determination of Se in Brazil nuts

CHED 196

Peter M. Schaber, schaber@canisius.edu1, Lori A. Shepherd, schaber@canisius.edu1, Harvey A. Pines, pines@canisius.edu2, Judith E. Larkin, larkin@canisius.edu2, and Elizabeth E. Wierchowski, wierchoe@canisius.edu1. (1) Department of Chemistry and Biochemistry, Canisius College, 2001 Main Street, Buffalo, NY 14208-1098, (2) Department of Psychology, Canisius College, 2001 Main Street, Buffalo, NY 14208
The first example of an effort to integrate the technique of fluorescence spectroscopy into analysis oriented courses at Canisius College is described. This case study considers an otherwise healthy individual that has been diagnosed with elevated Se in their system. Initial investigation leads to a possible diet connection. Student groups play the role of “research investigators” working for a facility associated with a local hospital, and analyze Brazil nuts (the leading suspect) for Se content. This case study exposes students to the technique of derivatization to enhance fluorescence intensity, the self absorption problem, use of microwave digestion, and a modified standard addition method. Student groups need to determine the concentration of Se in Brazil nuts, and determine if this concentration level poses a problem with respect to the levels found in the patient. Experimental design, student survey and assessment results are provided.
 

General Posters
7:30 PM-9:30 PM, Sunday, March 25, 2007 Hyatt Regency Chicago -- Riverside Center, Poster

Division of Chemical Education

The 233rd ACS National Meeting, Chicago, IL, March 25-29, 2007