Membrane bending mechanics and cellular signal transduction


Jay T. Groves,, Department of Chemistry, UC Berkeley, Howard Hughes Medical Institute, Berkeley, CA 94720
Signal transduction in living cells is carried out through cascades of chemical reactions, which generally begin on the cell membrane surface. In recent years, there has been growing realization that the spatial positions of cell surface receptor proteins influence and regulate the manner in which subsequent stages of chemical signaling cascades are triggered. In this talk, membrane bending mechanics will be discussed as a means of long-range coupling between cell surface receptor proteins. Such long-range interactions may affect the spatial organization of the receptors and, correspondingly, influence the ensuing signaling behavior.

Biological Surface Chemistry
8:30 AM-11:50 AM, Monday, March 26, 2007 McCormick Place South -- Room S404A, Level 4, Oral

Division of Colloid & Surface Chemistry

The 233rd ACS National Meeting, Chicago, IL, March 25-29, 2007