CHED 1629 |
| Exploring biosynthetic pathways and connections through total synthesis is a central theme of our research program. Several efficient syntheses of biologically active natural products that have been guided by biosynthetic speculations will be presented. In addition, small molecules that confer completely new functions to a central switch in neurobiology - the ionotropic glutamate receptor will also be discussed. Using a combination of chemical synthesis and site-directed mutagenesis we have developed a light-actuated version of this ion channel that mimics naturally occurring photoreceptors and has already found interesting applications in neurobiology. |
|
Exploring and Exploiting Nature with Biomimetics
1:30 PM-4:45 PM, Tuesday, March 27, 2007 McCormick Place North -- Room N230A, Level 2, Oral
Division of Chemical Education |