TOXIMonday, 11 September 2006

8:00 PM-10:00 PM Moscone Center -- Hall D, Sci-Mix
Sci-Mix
Organizer:Trevor M. Penning
 Conformation of a 14S(-)-trans-anti-dibenzo[a,l]pyrene diol epoxide-dG adduct in an 11-mer DNA duplex investigated by NMR methods
Fabian A. Rodriguez, Yijin Tang, Jane M. Sayer, Donald M. Jerina, Nicholas E. Geacintov
 Translesion synthesis by Sulfolobus solfataricus DNA polymerase Dpo4 across polycyclic aromatic hydrocarbon diol epoxide adducts of deoxyadenosine
Goutam Chowdhury, Hong Zang, Karen C. Angel, Thomas M Harris, F. Peter Guengerich
 Benzo[a]pyrene-mediated DNA-adduct formation in bronchoalveolar cells
Stacy Lynn Gelhaus, Qian Ruan, Seon Hwa Lee, Trevor M Penning, Ian A. Blair
 Detection of multiple DNA adducts in human lung and esophagus tissue by liquid chromatography electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS)
Robert A. Kanaly, Saburo Matsui, Tomoyuki Hanaoka, Tomonari Matsuda
 Induced CD/19F NMR characteristics as novel markers for arylamine-induced conformational heterogeneities
Fengting Liang, Nidhi Jain, Srinivasa Rao Meneni, Bongsup Cho
 Probing the aminofluorene-induced conformational heterogeneity by 2-aminopurine fluorescence studies
Nidhi Jain, Yana Reshetnyak, Bongsup Cho
 Structure and stability of duplex DNA containing a 3-(deoxyguanosin-N2-yl)-2-acetylaminofluorene (dG(N2)-AAF) lesion
Carlos De los Santos, Tanya Zaliznyak, Radha R Bonala, Francis Johnson
 Unraveling the aflatoxin-FAPY conundrum: Structural basis for differential replicative processing of isomeric forms of the formamidopyrimidine-type DNA adduct of aflatoxin B1
Thomas M. Harris, Kyle L. Brown, James Z. Deng, Rajkumar S. Iyer, Lalitha G. Iyer, Markus W. Voehler, Michael P. Stone, Constance M. Harris
 DNA adducts derived from carcinogenic aristolochic acids
Radha R Bonala, Sivaprasad Attaluri, Francis Johnson
 Different translesion bypass of guanine-N2 monoadducts of mitomycin C and guanine-N7 monoadducts of 2,7-diaminomitosene by DNA polymerase eta
Cristina Clement, Maria Tomasz
 Characterization and quantitation of 2'-deoxyguanosine adducts of the dietary carcinogen PhIP by linear quadrupole ion trap mass spectrometry
Angela K. Goodenough, Robert J. Turesky
 Mutagenic nucleotide incorporation and hindered translocation by a food carcinogen C8-dG adduct in Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): Modeling and dynamics studies
Ling Zhang, Olga Rechkoblit, Lihua Wang, Dinshaw J Patel, Robert Shapiro, Suse Broyde
 Characterization of a novel 8-oxo-guanine derivative of 4-hydroxyestradiol-1-N7-guanine
Leslie Machado, Alissa Rennie, Marlin D. Friesen, John D. Groopman
 In vitro and in vivo metabolism of the DNA base adduct, M1G
Charles G. Knutson, Brenda C. Crews, Donald F. Stec, Markus Voehler, Lawrence J. Marnett
 Structural characterization of DNA duplexes having exocyclic 2'-deoxyguanosine adducts
Carlos De los Santos, Tanya Zaliznyak, Radha R Bonala, Francis Johnson, Mark Lukin
 Base sequence effects on guanine oxidation by carbonate radical anions: Kinetics and gel electrophoresis studies
Young Ae Lee, Byeong Hwa Yun, Seog K Kim, Yelena Margolin, Peter C. Dedon, Nicholas E. Geacintov, Vladimir Shafirovich
 Stereoselectivity of repair and lifetime of C-3'-DNA radicals
Sanda Grosu, Georges Lahoud, Amanda C. Bryant-Friedrich
 UVA-induced oxidation of 6-thioguanine in mammalian cells
Chunang Gu, Yinsheng Wang
 Distribution of structurally defined oxidative guanine lesions along K-ras and p53 derived DNA sequences
Natalia Tretyakova, Brock Matter
 Interstrand crosslinks generated by abasic sites in duplex DNA
Sanjay Dutta, Kent S. Gates
 Kinetics of carboplatin-DNA binding in genomic DNA and bladder cancer cells as determined by accelerator mass spectrometry
Sang Soo Hah, Paul T. Henderson
 Disturbances in purine metabolism lead to substantial incorporation of hypoxanthine into DNA and RNA
Bo Pang, C. Eric Elmquist, Min Dong, Richard P. Cunningham, Peter C. Dedon
 Defining the spectrum of DNA, RNA and protein adducts arising from lipid peroxidation: A comprehensive approach
C. Eric Elmquist, Jimmy Flarakos, Rosa G. Liberman, Paul L Skipper, Steven R. Tannenbaum, Peter C. Dedon
 Lipid peroxidation-derived DNA adducts dominate the spectrum of DNA lesion chemistry in tissues from the SJL mouse model of nitric oxide over-production
Bo Pang, Xinfeng Zhou, Hongbin Yu, Min Dong, Steven R. Tannenbaum, Peter C. Dedon
 Correlation between hemoglobin adducts and DNA adducts following acrylamide and glycidamide exposures in Fischer 344 rats and B6C3F1 mice
Eden Tareke, Mona I. Churchwell, L. Patrice McDaniel, Nathan C. Twaddle, Daniel R. Doerge
 Fasicularin-derived aziridinium ion: Theoretical study of the formation of the putative reactive nitrogen species
Papiya Majumdar, Sanjay Dutta, Rainer Glaser, Kent S. Gates
 Bioactivation of the antitumor agent tirapazamine by thiols and dithiols
Venkatraman Junnotula, Delshanee Kotandeniya, Goutam Chowdhury, Kent S. Gates
 Amiodarone-induced cytotoxicity: Link to mitochondrial dysfunction and labile iron involvement
Adrian C. Nicolescu, Bruce C. Hill, James F. Brien, William J. Racz, Thomas E. Massey
 Cytotoxicity and mutagenicity of potential metabolites of 2,6- and 3,5-dimethylaniline and 3-ethylaniline
Hyun Gyung Jang, Laura J. Trudel, John S. Wishnok, Steven R. Tannenbaum, Gerald N. Wogan
 Structure-activity-bioactivation relationship studies on arzoxifene analogs
Zhihui Qin, Hong Liu, Cassia R. Overk, Ping Yao, Judy L. Bolton, Gregory R. J. Thatcher
 Novel agents for the redox regulation of protein tyrosine phosphatases
Jason LaButti, Thomas Reilly, Goutam Chowdhury, Kent S Gates
 Chemical reactions underlying the redox regulation of protein tyrosine phosphatase 1B (PTP 1B)
Santhosh Sivaramakrishnan, Kent S Gates
 Identification of nitrated tryptic peptides in complex biological systems using a specific immunoprecipitation method coupled with mass spectrometry
Jennifer R. Seal, John S. Wishnok, Steven R. Tannenbaum
 Teucrin A-induced changes in rat liver proteomes and identification of protein targets of teucrin A by MALDI-TOF MS and LC/MS/MS
Alexandra Druckova, Raymond L. Mernaugh, Amy Joan L. Ham, David B. Friedman, Lawrence J. Marnett
 Toxicological and structural features of KIAA1363: A novel detoxifying enzyme for organophosphorus nerve poisons
Daniel K. Nomura, Kathleen A. Durkin, Kyle P. Chiang, Gary B. Quistad, Benjamin F. Cravatt, John E. Casida
 In vitro evidence for mechanism based inactivation of P450 2E1 by 1,2-epoxy-3-butene
Gunnar Boysen, Nadia I Georgieva, Cameron O Scarlett, Brenda Temple, Christoph H Borchers, James Swenberg
 Metal oxide microspheres and nanoparticles: Preparation and toxicity evaluation
Won Hyuk Suh, Ah Ram Jang, Yoo-Hun Suh, Kenneth S. Suslick
 Investigations into the role of a radical mechanism employed by limonene hydroperoxides in allergic contact dermatitis
Timothy M. Altamore, Anna Börje, Ann-Therese Karlberg
 Towards the development of real-time detection of breath biomarkers from CBNR exposure
Stephen T. Hobson, Todd E. Mlsna, Sanjay V. Patel, Sabina Cemalovic

Symposium Grid -- Division of Chemical Toxicology -- Session Listing

The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006