BIOTTuesday, 12 September 2006

3:00 PM-5:30 PM Hilton San Francisco -- Plaza, Oral
Downstream Processing: Purification and Platform Case Studies
Organizers:Sam Guhan
Andrew Ramelmeier
3:00 PMPlatform approach to monoclonal antibody purification: Reality or myth?
Patricia Aldred, Rich Siegel
3:25 PMStrategies for rapid scale-up from bench to clinical manufacturing: Case study of a MAb
David J. Roush, N. Tugcu, F. Torres, K. Goklen
3:50 PMAnion exchange purification of monoclonal antibodies: Principals of weak partitioning chromatography
S Vunnum, Mary Switzer, R Godavarti, T Iskra, Paul R Brown, S Tobler, J Coffman, B Costigan, C Kha, D Wright, K Sterl, B Kelley
4:15 PMClearance of helper adenovirus by a platform AAV1 clinical vector manufacturing process
Paulene Quigley, Barbara A. Thorne, Gina Nichols, David N. Price, Christine Moore, Kristin Parker, Tsering Sangmo, Eric Pastor, Morgan Peterson, Ryan K. Takeya, Richard Peluso
4:40 PMUse of a flexible process template for purification of E. coli-derived recombinant proteins from Group A Streptococcus
John Xianfang Zeng, Joe Makowiecki, Jackie Puglisi, Yi Xiong, Stephen Standring, Greg Bunk, Prima Lukose, George Enriquez, Katia Liharska, Jonathan Seals
5:05 PMDevelopment of a purification process for a Phase I protein: A case study
John Pieracci, Richard Weber, Deanna Myers, John Hanson, Asif Ladiwala, Felicia Henderson, Matthew Beaulieu, Kim Bratberg, Eric Cunningham, Yuan Chang, Lynn Conley, Jorg Thommes

Previous Session -- Downstream Processing: Purification and Platform Case Studies

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The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006