| BIOT | Wednesday, 13 September 2006 | ||
5:30 PM-7:30 PM Moscone Center -- Hall D, Poster | |||
Poster Session | |||
| Downstream | |||
| Organizers: | Claire F. Komives Sanjeev Ahuja Chia Chi Ho | ||
| 297 | Suspension mixing studies for production scale hydroxyapatite column packing Michael A. Winters, Thomas J. Svab, Robert P. Kasprow, Michael J. Kosinski | ||
| 298 | Robustness of virus removal by Protein A chromatography is independent of media lifetime and mechanism of degradation Scott Lute, Lenore Norling, Michael Hanson, Qi Chen, Kurt Brorson | ||
| 299 | Displacer concentration effects in displacement chromatography: Proteomic applications Steven Taylor Evans, Alexander S. Freed, Amy Manocchi, Steve M. Cramer | ||
| 300 | Disposable POD depth filter evaluation Francisco Valles, Megumi Noguchi, Paul Bezy, Adema Arroyo, Brad Wolk, Marty Siwak | ||
| 301 | Evaluation of a disposable Q-membrane filter in the purification of a monoclonal antibody Keqiang Shen, Siegfried Rieble, Jay Leversee, Scott Gangloff, Eugene Schaefer | ||
| 302 | Flexible purification of histidine-tagged and untagged proteins using various metal ions and IMAC Sepharose 6 Fast Flow Johan Karlsson, Ellinor Ancker, Marianne Albenius, Lars C Andersson, Makonnen Belew | ||
| 303 | Impact of cell density and viability on primary clarification of mammalian cell broth Michael J. Iammarino, Joseph Nti-Gyabaah, Martin Chandler, David J. Roush, Kent E. Göklen | ||
| 304 | Improving the performance of chromatography columns using computational fluid dynamics Sanjib Das Sharma, L. Srinivasa Mohan, Richard D. LaRoche | ||
| 305 | J-Tube vs. Dip Tube: A manufacturing study designed to mininize the level of high molecular aggregates in the phenyl eluate for a IgG4 monolclonal antibody Carl Hitscherich Jr, Kevin Maloney, Ron Corey, Amin Aubjoub, James Weidner | ||
| 306 | Paper Withdrawn | ||
| 307 | Precipitation of plasmid DNA by cationic detergents: Interaction with buffer components and the use of modifiers to aid dissolution Matthew P. Watson, Sangeetha L. Sagar, Jason C. Murphy | ||
| 308 | Production and pilot scale recovery of bovine chymosin B from safflower seed W. Brent R. Pollock, Mitch Beazer, Joseph G. Boothe, Rick Keon, Maurice M. Moloney, Kent Shafer, Helen Yang | ||
| 309 | Protein purification using new high-capacity ion exchange resins Jon R. Fisher Jr., Martin Deetz, Amie S. Gehris, Boris Polanyer, John J. Maikner, Marlin K. Kinzey | ||
| 310 | Rapid removal of detergents from protein solutions using polymeric reversed phase resins Jon R. Fisher Jr., Amie S. Gehris, John J. Maikner | ||
| 311 | Selective removal of leached protein A, aggregates and host cell proteins from mAbs by multi-modal anion exchange chromatography Anders Ljunglöf, Eggert Brekkan, Annika Forss, Martin Antti | ||
| 312 | Sodium butyrate impacts the expression of genes associated with erythropoietin glycosylation Christopher K. Crowell, Gustavo Grampp, Qiang Qin, Gary N. Rogers, Richard A. Radcliffe, Robert Scheinman | ||
| 313 | Paper Withdrawn | ||
| 314 | Paper Withdrawn | ||
| 315 | A toolbox for efficient release of therapeutic proteins from the periplasm of Pseudomonas fluorescens Anant Patkar, Mike Chappell, Yuk Chun Chiu, Jeff Allen, Jefry Shields, Subrata Sen | ||
| 316 | Simulation of an industrial ion exchange step: The use of simulation for optimization Thomas Budde Hansen, Steffen Kidal | ||
| 317 | Affinity adsorption of viruses using small peptide ligands Caryn L Heldt, Patrick V. Gurgel, Ruben G. Carbonell | ||
| 318 | Analysis of mAb Protein A chromatography peak precipitates and approaches to reduce peak turbidity Scott A Tobler, Aaron Noyes, Joseph W. Rajewski III, Russell Shpritzer, Jon Coffman, Suresh Vunnum, Brian Kelley | ||
| 319 | Automation of a multi-dimensional chromatography lab model for the downstream purification of monoclonal antibodies William Holmes | ||
| 320 | Purification of ACE inhibitory peptide using synthetic cloned DNA as tandem multimers expressed in Escherichia coli Md. Fida Hasan, Yoichi Kumada, Masaaki Terashima, Shigeo Katoh | ||
| 321 | Binding kinetics of immunoglobulins on affinity membranes Cristiana Boi, Simone Dimartino, Giulio C. Sarti | ||
| 322 | Practical issues in the industrial use of hydroxyapatite for purification of monoclonal antibodies Pete Gagnon, Paul Ng, Julia Zhen, Jie He, Cheryl Aberin, Heather Mekosh | ||
| 323 | Analysis of adsorptive membranes for DNA clearance William T. Riordan, Mark R. Etzel | ||
| 324 | Binding of virus, DNA, and protein particles to anion exchange ligands: Kinetic and transport limitations assessed using surface plasmon resonance William T. Riordan, Mark R. Etzel | ||
| 325 | Inclusion body purification method increases protein refold efficiency four-fold for Human Aspartase-2 William A. Miller, Bruce F. Bishop, Stephen E. Sobacke, Marc H. Perez, Paul B. Lanter | ||
| 326 | Intermediate purification of a monoclonal antibody: Productivity maximization based on multivariate data analysis Mattias Bryntesson, Martin Antti, Carina Engstrand, Maria Murby, Gustav Rodrigo | ||
| 327 | Mixed-matrix-membrane alternative in bioseparations M. Omon Herigstad, Patrick V. Gurgel, Ruben G. Carbonell | ||
| 328 | Optimization of monoclonal antibody production using process simulation and scheduling tools Charles A. Siletti, Demetri Petrides | ||
| 329 | Process analytical technology (PAT) applications to unit operations used for the purification of biotech products A Sharma, Anurag S Rathore, David Chilin | ||
| 330 | Process demonstration of a new full-scale protein purification process Akhil Agrawal, Dicky Abraham, Dave Wohlpart | ||
| 331 | Process modeling in bioprocess development and technology transfer D. Petrides, Charles A. Siletti | ||
| 332 | Cation exchange chromatography (CEX) process development Jonida Basha, Nihal Tugcu, David J Roush, Kent E Goklen | ||
| 333 | Paper Withdrawn | ||
| 334 | Comparison of cation exchange resins using a therapeutic antibody: Experimental and theoretical studies Lyle R. Lash III, Chris J DeMello, Ajoy Velayudhan, Mark Teeters, Chiali Liu | ||
| 335 | Comparison of pH and protease stability of an alkali stabilized Protein A derivative with recombinant Protein A Tomas Björkman, Hans J. Johansson | ||
| 336 | Clustered-charge adsorbents with enhanced protein affinity and selectivity Sindhu Balan, Ajish SR. Potty, Richard C. Willson | ||
| 337 | Paper Withdrawn | ||
| 338 | Protein phase behavior in polymer solutions: Ovalbumin / PEG 8000 / (NH4)2SO4 and ovalbumin / PEG 8000 / NaCl André C. Dumetz, Eric W. Kaler, Abraham M. Lenhoff | ||
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The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006