BIOTWednesday, 13 September 2006

5:30 PM-7:30 PM Moscone Center -- Hall D, Poster
Poster Session
Upstream
Organizers:Claire F. Komives
Sanjeev Ahuja
Chia Chi Ho
Engineering mammalian host cell lines for reduced expression of lactate dehydrogenase
Yun Seung Kyung, Adam Campbell, Subinay Ganguly, Haimanti Dorai
Development of a robust and efficient technology transfer process for cell culture based biopharmaceuticals
Anurag Khetan, Ching Lee, Barbara Woppmann, Paul Chen, David Chang
Establishment of a cell culture bioreactor scale-down model for process qualification studies
Christoph E. Joosten
High-yield mAb expression: ACE system testing and process development
Erwin Y. Yu
Characterization of cholesterol and lipid content in PER.C6 ®Cell Membrane
Marie-Pierre Gentile, Nedim Emil Altaras, Aboli Rane
Enhancing the longevity of ion selective electrode arrays in bioreactors
Hajime Fuchida, Daniel C. Rieck, Bernard J. Van Wie, David A. Kidwell, William C. Davis
Metabolic engineering for enhanced phytochelatin production and heavy metal accumulation
Wonkyu Lee, Seung hyun Kang, Jae-Young Kim, Ashok Mulchandani, Wilfred Chen
Metabolic engineering leading to the combined production of vitamin B12 and folic acid in lactic acid bacteria
Filipe Santos, Arno Wegkamp, Eddy Smid, Willem M. de Vos, Jeroen Hugenholtz
Regulation of formaldehyde assimilation or dissimilation in Bacillus subtilis and thermotolerant Bacillus methanolicus MGA3
Matthew J Smith, Claire F. Komives, Nir Dover, Michael C Flickinger
Reorganization of enzyme activities for the design of novel biosynthetic pathways
Kristala Jones Prather, Amanda Lanza, Wei Chan
Transient expression in planta as a platform for rapid production of functional recombinant human therapeutic proteins
Michael A. Plesha, Ting-Kuo Huang, Mysore R. Sudarshana, Sandra L. Uratsu, Bryce W. Falk, Abhaya M. Dandekar, Alan P. Jackman, Karen A. McDonald
Preparation of lipases derivatives with high activity and stability by isopropanol treatment and immobilization on macroporous resin
Md. Mahabubur Rahman Talukder, Jinchuan Wu, Akihiko Kondo
Software calibration and data processing for ion selective electrode arrays used in applications with solutions of high ionic strength
Daniel C. Rieck, Bernie Van Wie, James M. Mullin, David A. Kidwell
Steroid biotransformations by Fusarium oxysporum var. cubense and the examination of its potential for C7-hydroxylation
Paul B. Reese, Patrice C. Peart
Transporter engineering for enhanced metabolic characteristics
Katie F. Wlaschin, Wei-Shou Hu
Cell engineering for hyperproductivity: Drawing insights from transcriptome and proteome analysis
Anne Kantardjieff, Gargi Seth, Wei-Shou Hu
Development of a low serum medium for culture of MRC-5 cells
Kirsten E. Lewus, Warren Pilbrough, Jennifer L. Zak, Lisa McCormick, Gargi Maheshwari
Development of a scalable transient transfection process in wave bioreactors
Jessica L. Okonkowski, Zubia Naji, Kristin Listner, Jason Murphy, Laura Kizer Bentley, Julia Markusen, Michel Chartrain
Development of an airlift bioreactor to measure specific productivity in CHO cell culture
Mark R Sanford, Lily Chu, Benjamin C. Pelletier
Development of powder-based feeds for large-scale NS0 cell culture
Neha B. Shah, Serena Fries, Kristin Listner, David K. Lee, Vanessa Kober, Melanie Tellers, Christine Chan, Peter M. Salmon, David Robinson, Michel Chartrain, Craig Seamans
Fermentation of acid pretreated corn stover to ethanol using Pichia stipitis
Frank Agbogbo
Flux analysis of anaerobic carbon metabolism in Shewanella oneidensis MR-1
Yinjie Tang, Adam Meadows, Jeannie Chu, Jay D. Keasling
Paper Withdrawn
Introduction of closed system spinner flasks to mitigate contamination
Ching Lee
Kinetic studies on a hybridoma cell line secreting NK mAb in a high density culture
A. Natasha Godwin, Christopher J. Detzel, William C. Davis, Bernard J. Van Wie
Novel use of a centrifugal bioreactor for cartilage tissue growth from isolated chondrocytes
Christopher J. Detzel, Howard L. Hosick, Bernard J. Van Wie
Optimization of fermentation process and media conditions to express small peptides
Renato Meneses, Brian Schmidt, Gopal Chotani
Prediction of blend time of a bioreactor for sparged and non-sparged conditions using computational fluid dynamics
John Straus
Prediction of oxygen mass transfer coefficients in bioreactors using multiphase flow simulations
John Straus, Alex Fotopoulos, Atul Gupta
Reducing high mannose glycoforms through process optimization
Jian Wu, Nicole Le, Michael de la Cruz
A chemically defined feed medium as a replacement for a peptone-containing feed maintains high levels of productivity from a mammalian cell culture process
Nicole Le, Jian Wu, Mike De La Cruz
Ammonium feeding enhances the production of bioactive metabolites (cordycepin and exopolysaccharides) in mycelium culture of a Cordyceps sinensis fungus
Po Hong Leung, Jian Yong Wu
Anaerobic fermentation of glycerol by E. coli: A proteomics study
Ashutosh Gupta, Ramon Gonzalez
Cell culture scale-up and start-up strategies for NIMO, Genentech's new manufacturing facility
Mahalia Corrales, Eric Fallon, Mickey Yraceburn, Christopher Makely, Matt Romeo, Soumitra Mishra
Baculovirus transduction of mammalian cells is hindered by sodium bicarbonate in the medium
Heng-Chun Sheng, Hsiao-Ping Lee, Yen-Lin Chen, Yi-Chen Ho, Yu-Chen Hu
Comparability study of inoculum performance from Wave Bioreactors® and small scale stirred bioreactors
Johnny I Andraous, Thomas T Black, Matt Livermore, Sigma S Mostafa
Comparison of disposable bioreactors with stirred-tank bioreactors and conventional cell expansion methods for CHO cells in a GMP facility
Jayanth Sridhar, Celeste Chang
Correlation of baculovirus-mediated gene delivery with cell cycle and extracellular matrix
Hsiao-Ping Lee, Yen-Lin Chen, Heng-Chun Sheng, Wen-Hsin Lo, Yu-Chen Hu
Development of a defined feed medium using a statistical approach to optimize recombinant protein expression
Michael De La Cruz, Jian Wu, Jeff Yant
Effect of composition on thawing of frozen protein and excipient solutions on 0.1 to 300 liter scale
W. Aaron Pruett, Samir Sane, Philippe Lam, Chung Hsu
Evaluation of batch, fed-batch and perfusion processes for astaxanthin (carotenoid) production in liquid cultures of Xanthophyllomyces dendrorhous
Yuan Shuai Liu, Jian Yong Wu
High yield Epothilone mutants of Sorangium cellulosum by genome shuffling
Lu Yiming, Luo Lixin, Pan Li
Medium and feed optimization in mammalian cell culture using online amino acid analysis
Michael Arulgnanendran, Polina Rapoport, Martin Gawlitzek, Kirin Jamison, Deborah E. Pascoe
Production of recombinant glycoprotein with low levels of N-glycoylneuraminic acid in Chinese hamster ovary cells by co-expressing CMP-sialic acid transporter
Dong Gyun Kang, Ji Eun Lee, Kyung Rho Kim, Hyung Joon Cha
Development and scale-up of perfusion cell culture process for therapeutic protein production
Jun Luo, Charles Bedard, WengLong Lin
Engineering heterologous drug metabolism in Gram negative bacteria
Jamie E. Prior, Tobin Strom, Uwe Christians, Ryan T Gill
Towards biorefineries and cellulosic ethanol or organic acids: Efficient production from mixed sugars by growth-arrested bioprocesses using Corynebacteria
Masayuki Inui, Shohei Okino, Masako Suda, Haruhiko Teramoto, Toru Jyojima, Alain A. Vertès, Hideaki Yukawa
Utilizing microfluidics for spatial control over cell attachment on biodegradable polymers
Aliasger K Salem
Chemically inducible Cucumber mosaic virus amplicon expression system for production of recombinant human proteins in transgenic plant cell cultures
Ting-Kuo Huang, Michael A. Plesha, Mysore R. Sudarshana, Sandra L. Uratsu, David M. Tricoli, Bryce W. Falk, Abhaya M. Dandekar, Alan P. Jackman, Karen A. McDonald
Design, construction and optimization of shotgun genomic DNA microarray to examine the Clostridium tyrobutyricum transcriptome
Yali Zhang, Xiaoguang Liu, Shang-Tian Yang
Development of potent chemically defined medium and on-line OUR for CHO-based, fed-batch processes
Terrence A. Allotta, Yao-ming Huang, Helena Yusuf-Makagiansar, David Chang
Effect of soybean trypsin inhibitor on Bacitracin fermentation
Kevin R. Jurgens
Effects of rapamycin and sodium butyrate on the transcription and translation of a monoclonal antibody
Tiffany D. Rau, R. Robert Balcarcel
Enhanced arsenic accumulation and removal by engineered yeast cells expressing arsR
Shailendra Singh, Dhawal Shah, Wonkyu Lee, Nancy A. Da Silva, Wilfred Chen
Identification of succinic acid tolerance genes in E.coli
Amarjeet Singh, Ryan T Gill
Investigation of novel latex micro-photobioreactor for hydrogen production using non-growing Rhodopseudomonas palustris mutants
Jimmy L. Gosse, Brian J. Engel, Michael C. Flickinger
Modeling of T-DNA transfer and resultant transient trangsene expression in agroinfiltrated leaf tissue
Christopher W. Simmons, Jean S. VanderGheynst
Novel system for heterologous protein expression in the yeast Kluyveromyces lactis
Paul Colussi, Jeremiah Read, Shamik Sharma, Barbara Taron, Chris Taron
Performance comparability of differently designed bioreactors
Keith L. White, Edmund G. Scarfo, Anuj S. Bhartiya, Eric Ordonez, Kiyomi Ross, Daniel R Lasko, Kathy Carswell, Robert Kiss
Process and metabolic engineering of Propionibacterium acidipropionici for enhanced propionic acid fermentation
An Zhang, Supaporn Suwannakham, Shang-Tian Yang
Process development of oxygenated oleochemicals from microbial conversion of plant lipids in batch cultures
Tsung Min Kuo, William E. Levinson

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The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006