ANYLTuesday, 12 September 2006

1:30 PM-5:00 PM Moscone Center -- Room 124, Oral
Methods Development for Pharmaceutical Analysis
Organizer, Presiding:Terri L. Quenzer
1:30 PMAdventures in developing a ligand binding assay for the c-Met Kinase: NMR to the rescue
Gordon Alton, Cathy Moore
2:00 PMSupercritical fluid chromatography reduces back exchange after solution-phase hydrogen/deuterium exchange
Mark R. Emmett, Sasa Kazazic, Alan G. Marshall, Wei Chen, Stone. D. Shi, Ben Bolaņos, Michael J. Greig
2:30 PMSite determination of tyrosine-O-sulfation resulting from tyrosylprotein sulfotransferases
Yonghao Yu, Julie A. Leary
3:00 PMIntermission
3:30 PMAdding value to NMR-based fragment screens by using competition binding or functional assays
Brian J. Stockman
4:00 PMStrategies for systematic HPLC method development
Thomas Jupille, John Dolan
4:30 PMScreening for reactive drug metabolites during early pharmaceutical drug discovery
John R Soglia

Symposium Grid -- Division of Analytical Chemistry -- Session Listing

The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006