| BIOL | Wednesday, 13 September 2006 | ||
4:30 PM-6:30 PM Moscone Center -- Hall D, Poster | |||
Enzymes | |||
| Organizers: | Tadhg Begley Karen N. Allen | ||
| 183 | α-cFaPydG: Synthesis, replication and repair Florian Büsch, Prof. Thomas Carell | ||
| 184 | Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase: Relevance of Thr463 and Arg457 for nucleotide binding and catalysis Ivan Tobar, Jaime A Rivas-Pardo, Felipe Arenas, Ana M. Jabalquinto, Emilio Cardemil | ||
| 185 | A chemoinformatics approach to the classification of enzymatic reactions Joao Aires-de-Sousa, Diogo A. R. S. Latino | ||
| 186 | A hydrophobic tunnel is important for the binding of molecular oxygen and subsequent catalysis by cholesterol oxidase Lin Chen, Nicole S. Sampson | ||
| 187 | Paper Withdrawn | ||
| 188 | A theoretical study of site-directed spin labeling of subtilisin Carlsberg in organic solvents Marc D. Legault, Gabriel L. Barletta, Vibha Bansal | ||
| 189 | Ab initio molecular dynamics reveals striking reorganization of the trinuclear metal cluster of endonuclease IV during catalysis Ivaylo Ivanov, John A. Tainer, J. Andrew McCammon | ||
| 190 | Activation of orotidine 5'-monophosphate decarboxylase by exogenous inorganic oxydianions Krisztina Toth, Tina L. Amyes, John P. Richard | ||
| 191 | Au(I)-Based inhibition of cysteine proteases: A structural and mechanistic investigation Mark R. Karver, Amy M. Barrios | ||
| 192 | Catalysis by flavin-dependent thymidylate synthases Bruce A. Palfey, Mehran Ebadi-Tehrani, Samuel G. Gattis | ||
| 193 | Catalysis-based selection system as a tool for identifying xylanase mutants with novel (or improved) catalytic properties David T Fox, Spencer J Williams, Stephen G. Withers | ||
| 194 | Catalytic metal ion switching: A new perspective on “zinc”-dependent deacetylases Samuel G. Gattis, Marcy Hernick, Stephanie L. Gantt, Carol A. Fierke | ||
| 195 | Catalytically active monomeric human histidine triad nucleotide binding protein 1 (hHint1) engineered by a single amino acid substitution Tsui-Fen Chou, Ilya B. Tikh, Carston R. Wagner | ||
| 196 | Characterization and effect mechanism of agarolytic enzymes from Chlorostoma rusticum Wenjun Mao | ||
| 197 | Characterization of a bi-functional protein with hemolysin and ABC transporter activity Yu Kuo Wang, Tung Kung Wu | ||
| 198 | Characterization of GlfT, a mycobacterial UDP-galactofuranosyl transferase John F. May, Christine Brotschi, Laura L. Kiessling | ||
| 199 | Characterizing the mechanism of Dpo4 polymerase bypass of O6-alkyl-guanine adducted DNA Robert Lawton Eoff, Hong Zang, F. P. Guengerich | ||
| 200 | Cobalamin-dependent methionine synthase conformation is governed by the ligand trans effect Angela S. Fleischhacker, Rowena G. Matthews | ||
| 201 | Combinatorial modulation of protein prenylation Amanda J. Krzysiak, Sarah A. Reigard, Diwan S. Rawat, Katherine A. Hicks, Carol A. Fierke, Richard A. Gibbs | ||
| 202 | Comparative study of colorimetric methods for analysis of water-soluble and immobilized proteins and peptides Nataliya M. Samoshina, Vyacheslav V. Samoshin | ||
| 203 | Comparative study of properties, immobilization, and applications of fungal glycosidases Nataliya M. Samoshina, Vyacheslav V. Samoshin | ||
| 204 | Computational methods for the directed evolution of Chondroitinase B Refugio Alvarez, Daniel V. Gil, Mark J Olsen | ||
| 205 | Cysteine based ferrocenyl peptides as heavy metal sensors Conor Scully, Peter J. Rutledge | ||
| 206 | Development and application of the first colorimetric poly(ADP-ribose)polymerase (PARP) substrate Amanda C. Nottbohm, Robin S. Dothager, Karson S. Putt, Mirth Hoyt, Paul J. Hergenrother | ||
| 207 | Discovery of novel inhibitors of Sortase A from Staphylococcus aureus by virtual screening Matthew L. Bentley, Sarah E. Chobot, Dewey G. McCafferty | ||
| 208 | DNA sequence selectivity and kinetic properties of de novo designed chimeric dimmers: Are two better than one? Siu Wah Wong-Deyrup, Dr. Sonya J Franklin | ||
| 209 | Docking P47phox PX domain on an interfacial membrane Kepeng Che, Alyssa L. Smith, Robert D. Nielson, Michael H. Gelb, Bruce H. Robinson | ||
| 210 | Dramatic solvent and hydration effects on the transition state of soybean peroxidase Anne L Serdakowski, Jonathan S. Dordick | ||
| 211 | DYNAPRED: Combining docking and sequence based methods for the prediction of MHC/peptide complexes for vaccine design Iris Antes, Shirley WI. Siu, Thomas Lengauer | ||
| 212 | Effect of cadmium on cysteine biosynthesis for Arabidopsis thaliana and Brassica juncea Ryo Hasegawa, Jane G. DeWitt | ||
| 213 | Energetics of the three predominant tautomers of 2-oxo-6-methylpurine, a slowly reacting substrate of xanthine oxidase Jong Hwa Kim, Taryn Hartley | ||
| 214 | Engineered biosynthesis of plant polyketides Tsuyoshi Abe, Satoshi Oguro, Hiroshi Noguchi, Ikuro Abe | ||
| 215 | Enzymatic characterization of human 15-lipoxygenase-2 and its splice variants Aaron T. Wecksler, Joshua D. Deschamps, Theodore R. Holman | ||
| 216 | Enzymatic synthesis of unnatural novel cyclic polyprenoids by bacterial squalene cyclase Hisashi Noma, Hideya Tanaka, Hiroshi Noguchi, Ikuro Abe | ||
| 217 | Enzyme mimics for the bioremediation of polycyclic aromatic hydrocarbons Sarah M. Barry, Peter J. Rutledge | ||
| 218 | Evidence for participation of remote residues in the catalytic activity of nitrile hydratase Heather Brodkin, Amy C. Milne, Mary Jo Ondrechen, Dagmar Ringe | ||
| 219 | Paper Withdrawn | ||
| 220 | Expression and secretion of Clostridium cellulovorans XynA in Saccharomyces cerevisiae Sarah B. Batt, Dominic W. S. Wong, Kurt Wagschal, Charles C. Lee | ||
| 221 | Flex-Hets inhibit electron transport in isolated human ovarian cancer cells: A possible prelude to apoptosis William J. Kelly, Lance W. Gill, Doris M. Benbrook | ||
| 222 | Functional analysis of polymorphic CYP1B1 allelic variants in African-Americans and their effects on the metabolism of (-)-benzo[a]pyrene-trans-7,8-dihydrodiol (B[a]P-7,8-diol) Mostafizur Rahman, Victor R. Kelley, Carrie Hayes Sutter, Gary L. Emmert, Paul T. Strickland, Douglas A. Bell, Thomas R. Sutter | ||
| 223 | Geosmin biosynthesis. Streptomyces coelicolor germacradienol/germacrene D synthase converts farnesyl diphosphate to geosmin Jiaoyang Jiang, Xiaofei He, David E. Cane | ||
| 224 | Glucocorticoid receptor: A disturbing element in the HPA axis negative feedback loop during stress response Shakti Gupta, Eric Aslakson, Brian M. Gurbaxani, Suzanne D. Vernon | ||
| 225 | Glycosyltransferase substrate engineering: Broadening the synthetic utility of enzymatic catalysis by facilitating productive binding modes for alternative substrates Luke L. Lairson, Andrew G. Watts, Warren W. Wakarchuk, Stephen G. Withers | ||
| 226 | Identification of proteins from the yeast haploid deletion library involved in Fre1 activity: Novel involvement of Pho85 and Avl9 in Mac1 activation Alisha Thompson, Xiaoli Shi, Ted Holman, Zhu Zhiwu | ||
| 227 | Imaging transcription Hua Yu, Kyubong Jo, David C. Schwartz | ||
| 228 | Improved model for peptidyl transfer in the ribosome Gottfried K. Schroeder, Richard V. Wolfenden | ||
| 229 | In vitro translation of unnatural cyclic peptides Matthew C. T. Hartman, Kristopher Josephson, Jack W. Szostak | ||
| 230 | Inhibition of Eschericia coli RecA by a rationally designed peptide helix Daniel J Cline, Scott F Singleton | ||
| 231 | Inhibitor binding to a distal active site region of bovine plasma amine oxidase selectively blocks metabolism of polyamine but not short-chain monoamine substrates Yanwen Chen, Bo Zhong, Lawrence M. Sayre | ||
| 232 | Inhibitors and inactivators of Protein Arginine Deiminase 4: Functional and structural characterization Yuan Luo, Kyouhei Arita, Monica Bhatia, Bryan Knuckley, Young-Ho Lee, Michael R. Stallcup, Mamoru Sato, Paul R. Thompson | ||
| 233 | Insights on replication of xDNA and yDNA by DNA polymerases Haige Lu, Haibo Liu, Jianmin Gao, Alex Lee, Sandra A. Helquist, Shin Mizukami, Eric Kool | ||
| 234 | Interacting AcpM with InhA, the enoyl–ACP reductase from M. tuberculosis Xujie Zhang | ||
| 235 | Investigation of a chromate reductase in a Psuedomonas veronii bacteria cell Michelle R. A. Stewart | ||
| 236 | Investigation of new potential substrates for Saccharomyces carlsbergensis Old Yellow Enzyme Magdalena A. Swiderska, Jon D. Stewart | ||
| 237 | Leaving-group substituent effects on DNA polymerase beta catalysis and fidelity Christopher A. Sucato, Thomas G. Upton, Boris A. Kashemirov, Charles E. McKenna, Arieh Warshel, Jan Florian, Samuel H. Wilson, Myron F. Goodman | ||
| 238 | Linking docking domains and substrate sequences: The design, synthesis, and evaluation of a selective p38a MAP kinase substrate Denise E. Bailey, Nancy Allbritton, David L. Van Vranken | ||
| 239 | Magnetic nanoparticle-supported enzymes as recyclable biocatalysts Aimee R. Herdt, Byeong-Su Kim, T. Andrew Taton | ||
| 240 | Measurement of primary 14C and α-secondary 3H kinetic isotope effects to probe the chemical transition state of the farnesyltransferase reaction June E. Pais, Katherine E. Bowers, Carol A. Fierke | ||
| 241 | Mechanism of potassium activation of IMP dehydrogenase Thomas Riera, Lizbeth Hedstrom | ||
| 242 | Mechanistic studies of a flavin-dependent Thymidylate Synthase Todd J Fleischmann, Nitish Agrawal, Amnon Kohen | ||
| 243 | Mechanistic studies of isothermal DNA amplification through polymerase and nicking enzyme activities Eric Tan, Megan Buechel, Barbara Erwin, Shale Dames, Karl Voelkerding, Angelika Niemz | ||
| 244 | Modulation of mammalian DNA methyltransferase activity by RNA Matthew M. Purdy, Norbert O. Reich | ||
| 245 | Mutagenesis and NMR insights into the mechanism of UDP-galactopyranose mutase Todd D. Gruber, Laura L. Kiessling | ||
| 246 | New strategies for the bioremediation of cyanide and nitrile contaminants Kate Houlihan, Peter J. Rutledge | ||
| 247 | Nitration of phenol catalyzed by horseradish peroxidase Rongji Dai, Hui Huang, Bin Tong, Weiwei Meng, Yulin Deng | ||
| 248 | Novel inhibitors for fungal glycosidases Barbora Brazdova, Nataliya M. Samoshina, Vyacheslav V. Samoshin | ||
| 249 | Novel oxidative pathways involved in the biosynthesis of rebeccamycin and staurosporine Annaleise R. Howard-Jones, Christopher T. Walsh | ||
| 250 | Peroxide-dependent oxidative degradation of halophenols catalyzed by heme proteins: From globins to peroxidases Robert L. Osborne, Michael K. Coggins, John H. Dawson | ||
| 251 | Photoacoustic study of ligand dissociation from lactoperoxidase Dustin Lockney, Jaroslava Miksovska | ||
| 252 | Phylogenetic differences in the mechanism of dihydroorotate oxidation by dihydroorotate dehydrogenases Rebecca L. Fagan, Paul M. Pagano, Maria N. Nelson, Bruce A. Palfey | ||
| 253 | Physical organic studies inside the membrane-embedded bacterial enzyme PagP Fraser Hof, Aaron H. McKie, Soizic Wadge, Olga V. Sarytcheva | ||
| 254 | Polyphenolic inhibition of vascular NADPH oxidase Jingjing Yu, Disha Ahuja, Michel Weïwer, Robert J. Linhardt, Jonathan S. Dordick | ||
| 255 | Probing the catalytic mechanism of human histone deacetylase 8 Stephanie L. Gantt, Carol A. Fierke | ||
| 256 | Paper Withdrawn | ||
| 257 | Profiling substrate specificities of protein tyrosine phosphatases: Toward the development of highly selective inhibitors Sayantan Mitra, Amy M. Barrios | ||
| 258 | Proton coupled electron transfer in co-mixed valence cytochrome C oxidase Randy Larsen | ||
| 259 | Quantification of reaction rates in the E. coli Min system Steven S Andrews, Adeleh Mazloom Moghaddam, Jay T. Groves | ||
| 260 | Rational redesign of the specificity of Sortase A from Staphylococcus aureus Matthew L. Bentley, Helena Gaweska, Dewey G. McCafferty | ||
| 261 | Reaction-diffusion kinetics of enzymes immobilized within a gel pad microarray Chao-Jen Wong, Modesto Lopez, Eric Tan, Ali Nadim, Angelika Niemz | ||
| 262 | Recognition and binding mechanisms of the DNA repair enzyme, MutY: A molecular dynamics study J. Samuel Arey, Ursula Rothlisberger | ||
| 263 | Recombinant enzymes over-expressed in bacteria show broad catalytic specificity of human cytochrome P450 2W1 and limited activity of human cytochrome P450 2S1 Zhong-Liu Wu, Christal D. Sohl, Tsutomu Shimada, F. Peter Guengerich | ||
| 264 | Reduction of 4-nitrophenol catalyzed by nitroreductase Rongji Dai, Jie Chen, Bin Tong, Weiwei Meng, Yulin Deng | ||
| 265 | Paper Withdrawn | ||
| 266 | Rheumatoid arthritis and gold(I): A mechanistic investigation into the inhibition of lysosomal cysteine proteases by a series of linear Au(I) complexes Shamila S. Gunatilleke, Amy M. Barrios | ||
| 267 | Role of heme-protein covalent bonds in mammalian peroxidases revealed by horseradish peroxidase F41E mutant Liusheng Huang, Grzegorz Wojciechowski, Paul R. Ortiz de Montellano | ||
| 268 | Stabilizing and catalytic roles of six secondary active site residues in E. coli chorismate mutase and implications for computational enzyme design Jonathan Kyle Lassila, Jennifer R. Keeffe, Stephen L. Mayo | ||
| 269 | Structure and function of the Bordetella bronchiseptica CAE protein of the haloalkanoate dehydrogenase superfamily Henry Nguyen, Liangbing Wang, Debra Dunaway-Mariano, Karen N. Allen | ||
| 270 | Studies of the reaction mechanism of phosphate hydrolysis in the ras-GAP proteins and in aqueous model systems Edina Rosta, Marco Klahn, Arieh Warshel | ||
| 271 | Study the correlation between parameters of lipid exchange and their ferment groups in patients ill with cystic vaginal fistula Jamshid Nurullayev, Nurali Q. Mukhamadiev, Shuhrat M. Sayitkulov | ||
| 272 | Paper Withdrawn | ||
| 273 | Synthesis of biliverdin amides and substrate specificity for Bacteriophytochromes and Bilin reductases Lixia Shang, J Clark Lagarias | ||
| 274 | Targeting RecA to prevent the evolution of antibiotic resistance: HTS-screening strategies and ATP-competitive inhibitors Tim J. Wigle, Andrew M. Lee, Scott F Singleton | ||
| 275 | Temperature dependent free energy profiles of alanine racemase from Staphylococcus aureus Shara K. Compton, Michael D. Toney | ||
| 276 | The iroA gene cluster: The latest step in an evolutionary arms race Michael A. Fischbach, Hening Lin, Kelly D. Smith, David R. Liu, Christopher T. Walsh | ||
| 277 | Traceless immobilization of proteins onto solid supports using protein trans-splicing Youngeun Kwon, Mathew A. Coleman, Julio A Camarero | ||
| 278 | Transition state analog discrimination by related purine nucleoside phosphorylases Erika A Taylor, Gary Evans, Peter C. Tyler, Richard H. Furneaux, Andrew S. Murkin, Vern L. Schramm | ||
| 279 | Trapping the catalytic complex of polymerase eta with a template primer by site-specific DNA protein disulfide crosslinking Dan Gu, J. S. Taylor | ||
| 280 | Two distinct proton donors at the active site of E. coli 2,4-dienoyl-CoA reductase are responsible for the formation of different products Xi Tu, Paul A. Hubbard, Jung-Ja Kim, Horst Schulz | ||
| 281 | Uncovering enzymatic mechanisms through ultra-high resolution structures Yu Chen, Brian K. Shoichet | ||
| 282 | Understanding general acid-base catalysis of enzyme-catalyzed reactions from computer simulations: Serine-carboxyl peptidases Hong Guo, Haobo Guo, Qin Xu, Alex Wlodawer | ||
| 283 | Understanding the biological activity of protein tyrosine phosphatases using peptide inhibitors containing Phosphonomethyl phenylalanine Caitlin E Hubbard, Amy M. Barrios | ||
| 284 | Using immobilized enzymes to study substrate specificity and free radical chemistry Bradley E Sturgeon | ||
Symposium Grid -- Division of Biological Chemistry -- Session Listing
The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006