| TOXI | Tuesday, 12 September 2006 | ||
2:00 PM-5:15 PM Moscone Center -- Room 308, Oral | |||
Drug Toxicity & Safety Prediction | |||
| Organizers: | F. P. Guengerich Nicholas A. Meanwell | ||
| 2:00 PM | 41 | Strategies to reduce drug candidate failure due to off-target activities Bruce D. Car | |
| 2:45 PM | 42 | Structural basis of drug binding to hERG K+ channels Michael C Sanguinetti | |
| 3:30 PM | Intermission | ||
| 3:45 PM | 43 | Properties of the hERG potassium channel that promote promiscuous binding of small organic molecules Robert Pearlstein, Ramy Farid, Tyler Day, Richard Friesner | |
| 4:30 PM | 44 | The hERG channel: Tuned in? Chemical strategies for dialing out an off-target source of candidate failure Brian Springhthorpe | |
Symposium Grid -- Division of Chemical Toxicology -- Session Listing
Symposium Grid -- Drug Discovery -- Session Listing
The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006