Lab-on-DVD: Concept and feasibility demonstration for water analysis

ANYL 254

Radislav A. Potyrailo, potyrailo@crd.ge.com, William G. Morris, morris@crd.ge.com, and Andrew M. Leach, leach@research.ge.com. Materials Analysis and Chemical Sciences, GE Global Research Center, 1 Research Circle, Niskayuna, NY 12309
We demonstrate a new approach for quantitative chem/bio sensing when analog signals are acquired from conventional optical drives and these signals are used for quantitative detection of optical changes of sensor films deposited on conventional CDs and DVDs. Because we do not alter manufacturing process of optical disks, any disk can be employed for deposition and readout of sensor films. The optical drives also perform their original function of reading/writing digital content to disks because no optical modifications are introduced to obtain analog signal. We demonstrate the concept using chemical detection of ionic species such as Ca2+ in liquids using colorimetric calcium-sensitive sensor films deposited onto a DVD, exposed to water with different concentrations of Ca2+ and simply quantified in the optical drive. The developed Lab-on-DVD system demonstrated a 5 ppm detection limit of Ca2+ determinations, similar or slightly better to that achieved using a conventional fiber-optic portable spectrometer.