Nanostructures integrated into BioMEMS devices

ANYL 334

Robin L. McCarley, tunnel@lsu.edu1, Guofang Chen, gchen@lsu.edu1, Stephen A. Soper, chsope@lsu.edu1, and Jowell G. Bolivar2. (1) Department of Chemistry, Louisiana State University, 232 choppin Hall, Baton Rouge, LA 70803, (2) Department of Chemistry, Louisiana State University, Baton Rouge, 306 Choppin Hall, Louisiana State University, Baton Rouge, LA 70803
Discussed here is the formation of nm-thick chemically modified regions, and nm- to mm-tall, nm-diameter polymeric nanostructures integrated into polymeric biomicroelectromechanical systems (BioMEMS) for use in miniaturized analytical devices. It is of great importance to make polymeric MEMS devices widely applicable to bioanalysis, for the inherent advantages of polymer-based MEMS are great. To this end, described here are solution- and gas-phase methods for the bulk and localized formation of chemically modified regions in polymer-based BioMEMS devices, such as those composed of poly(methyl methacrylate) and poly(carbonate). In addition, the need for integrated sub-micron scale features within microfluidic vias comes from applications that require high-surface-area detection strategies (arrays, immunoassays), highly efficient separation methods (CEC, sieving), and fast kinetics for mediated reactions (enzymes). Shown here is a technique for fabrication of hybrid nano/micro devices made from polymers using simple methods than can be utilized in the typical laboratory.
 

Analytical Approaches: Novel Materials
1:30 PM-4:40 PM, Thursday, 14 September 2006 Moscone Center -- Room 130, Oral

Division of Analytical Chemistry

The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006