Solid-state near-infrared (NIR) spectrometer based on a digital micromirror array device (DMD) for in-vitro measurement of glucose in binary mixtures

ANYL 268

Dong Xiang, dongx_s@yahoo.com1, Michael J. Miller, michael-miller@uiowa.edu2, Jonathon T. Olesberg, jonathon-olesberg@uiowa.edu1, Wenjiao Lin, wenjiao-lin@uiowa.edu1, Jianchuan Zhang, jianchuan-zhang@uiowa.edu3, and Mark A. Arnold, mark-arnold@uiowa.edu1. (1) Department of Chemistry and Optical Science and Technology Center, University of Iowa, Iowa City, IA 52242, (2) Physics & Astronomy, University of Iowa, B04 VAN, Iowa City, IA 52242, (3) Electrical and Computer Engineering, University of Iowa, 4016 SC, Iowa City, 52242
The major advantage of a solid-state spectrometer is no moving parts, which makes it possible for the system to be rugged, durable, and reliable. A novel solid-state spectrometer system is developed to achieve NIR measurements in the spectral region of 1480-1880nm. The centerpiece of this spectrometer is a digital micro-mirror array device that permits programmed selection of transmitted wavelengths. Operation of the system as a Hadamard transform spectrometer and a tunable filter spectrometer is demonstrated. Fundamental properties of the DMD spectrometer are evaluated including spectral resolution, noise, photometric linearity and chemical imaging capability. Analytical performance of this prototype spectrometer is demonstrated with both Hadamard transform spectra and tunable filter inputs for a set of glucose/lactate binary mixtures. Hadamard spectra result in calibration models with standard errors of 1.3 and 0.7mM for glucose and lactate, respectively, while filter data provide measurement errors of 1.2mM for both glucose and lactate.
 

Analytical Approaches, Spectroscopy
8:30 AM-12:00 PM, Wednesday, 13 September 2006 Moscone Center -- Room 124, Oral

Division of Analytical Chemistry

The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006