Cross-linked polymers by chemoenzymatic polymerization

POLY 393

Andreas Heise, andreas.heise@dsm.com1, Joris Peeters2, Yan Xiao, y.xiao@TUE.NL1, Anja RA. Palmans2, and Cor Koning, c.e.koning@tue.nl3. (1) Department of Polymer Chemistry, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, Netherlands, (2) Laboratory of Macromolecular and Organic Chemistry, Eindhoven University of Technology, P.O. Box 513, Eindhoven, 5600 MB, Netherlands, (3) Laboratory of Polymer Chemistry, Eindhoven University of Technology, P.O. Box 513, Eindhoven, 5600 MB, Netherlands
The chemoenzymatic synthesis of branched and cross-linked polymers was carried out following two approaches: In the first approach heterotelechelic polycaprolactone macroinimer was synthesized in a one-pot enzymatic procedure by using 2-hydroxyethyl bromoisobutyrate as a bifunctional initiator. A polymerizable end-group was introduced by subsequent in-situ enzymatic acrylation with vinyl acrylate. The degree of end-group functionalization of the polycaprolactone macroinimer can be controlled by the reaction conditions, i.e., concentration of water and acylating agent, respectively. Self condensing atom transfer radical polymerization (ATRP) of the macroinimers was successfully conducted with and without the addition of MMA as a comonomer to yield branched polymers. In a second approach enzymatically obtained di-hydroxy functionalized polycaprolactone was acrylated. The diacrylate was crosslinked to micropherical particles in an emulsion type reaction.
 

Biocatalysis in Polymer Science
1:30 PM-4:45 PM, Tuesday, 12 September 2006 San Francisco Marriott -- Salon 12/13, Oral

Division of Polymer Chemistry

The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006