Inorganic nanotubes, nanofluidic transistors and DNA translocation

PMSE 230

Peidong Yang, p_yang@berkeley.edu, Department of Chemistry, University of California, Berkeley and Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720
Inorganic nanotubes, representing a new class of nanostructures, have been attracting considerable attention during the past few years. Great success has been achieved in chemical synthesis of inorganic nanotubes from a variety of functional materials, including semiconductors, insulators and metals. Single crystalline semiconductor GaN nanotubes can be synthesized by nanowire templated epitaxial casting method. Partial conversion of existing nanowires leads to the synthesis of silica nanotubes after etching off remaining cores. Silica nanotubes can be integrated into metal-oxide-solution field effect transistors (MOSolFETs) which exhibit rapid field effect modulation of ionic conductance. Surface functionalization can change inherent carrier concentration as well channel polarity to fabricate p-type, n-type and ambipolar transistors. These nanofluidic devices were further demonstrated to be useful in single molecule sensing. Single DNA molecules can be electrically detected either by charge effect or geometry effect. These nanofluidic FETs have potential implications in sub-femtoliter analytical technology and large-scale nanofluidic integration.