ANYL 135 |
| The past ten years have witnessed tremendous advances in the design and use of microelectromechanical systems (MEMS). Applications for microfluidic devices (MDs) have proliferated at a speed reminiscent of microelectronics after the integrated circuit was invented. One area that microfluidic systems have been used successfully is in capillary electrophoresis (CE). CE utilizes differences in charge-to-mass ratios to afford separation of chemical species. CE and microfluidic systems are congruent in terms of volume requirements. The development of a high-throughput technique that couples both CE and microfluidics would be of great interest to scientists eager to exploit the power of both techniques. Herein, we report the use of MDs constructed by multilayer soft lithography (MSL) and poly(dimethylsiloxane) (PDMS) in the separation of small biological materials. By automating the sample introduction method whereby pressure and voltage are coupled to each other, separation of chemical species is expedited as compared to traditional commercial instruments.
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General Papers
7:00 PM-9:00 PM, Sunday, 10 September 2006 Moscone Center -- Hall D, Poster
Division of Analytical Chemistry |