ANYL 162 |
| In the United States alone, there are at least 5 million gastrointestinal endoscopies per year. Between endoscopies, the devices are cleaned and disinfected to a degree that is related to the proficiency of the endoscopy technician. As failure to appropriately clean endoscopes can result in significant risk of person-to-person transmission of pathogens, evaluation of the effectiveness of endocscope cleaning procedures is an important aspect of clinical hygiene. In the current study, a novel application of fluorimetric quantitation of proteins is presented, which provides unparalleled limits of detection for patient residues within endoscopes. Using a simple extraction paired with reactive fluorimetric quantitation, a detection limit of 140 parts-per-billion was achieved. Excellent linearity and recoveries were noted for several clinically recognized surrogate soils in the range of 750-ppb to 20-ppm. Though endoscopes were chosen as a model lumened device, the technique is broadly applicable to both lumened and non-lumened medical devices. |
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General Papers
7:00 PM-9:00 PM, Sunday, 10 September 2006 Moscone Center -- Hall D, Poster
Division of Analytical Chemistry |