ANYL 1 |
| The overall emphasis of our research efforts has been to develop analytical methods to sensitively measure neurochemicals with great temporal and/or spatial resolution and to use these methods to further understand a frontier area of science - the cell-to-cell functioning of the brain. In this talk the focus will be on recent attempts to use capillary electrophoresis techniques to examine brain chemistry. Eelectrophoresis in nanometer capillaries coupled to amperometric detection has been developed to quantify dopamine in single mammalian cell cytoplasm analyzing volumes as small as 80 femtoliters. In addition, micellar solutions have been employed with a borate buffer to separate 15 neurotransmitters and their metabolites from the 8-nL head of the fruit fly, Drosophila melanogaster. This work is aimed at developing new instrumentation and approaches to further our understanding the role of biogenic amines in drug tolerance and learning and memory. |
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Honoring Andrew Ewing, Recipient of the Chemical Instrumentation Award
8:30 AM-10:50 AM, Sunday, 10 September 2006 Moscone Center -- Room 123, Oral
Division of Analytical Chemistry |