BIOT 116 |
| Research in our laboratory is directed towards the structural biology of integral membrane proteins. We have pursued (and are pursuing) active methods-development efforts in multiple areas of membrane protein structural biology, e.g., expression, purification, characterization, crystallization and crystallography. Many aspects of these individual areas can be viewed as screening steps, and the assembly of these areas into a tractable manageable whole constitutes a process (or pipeline). Elements of this (narrow-bore) pipeline will be described. Current foci of the lab are bacterial TonB-dependent outer membrane transport, and human integral membrane proteins of biomedical & biotechnological interest. |
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Biophysical and Biomolecular Symposium: Challenges to Membrane Protein Production and Characterization
3:00 PM-5:30 PM, Monday, 11 September 2006 Hilton San Francisco -- Imperial B Ballroom, Oral
Division of Biochemical Technology |