Biscationic single chained amphiphiles with chiral and achiral counterions

CHED 290

Karolina Z. Roszak, roszakkz@jmu.edu, Kristen R. Donnelly, donnelkr@jmu.edu, David M. Crizer, crizerdm@jmu.edu, and Kevin L. Caran, carankl@jmu.edu. Department of Chemistry, James Madison University, MSC 4501, Harrisonburg, VA 22807
While a broad diversity of amphiphiles is readily available, there remains the need to continue to explore new systems that will expand the utility and specificity of colloidal aggregation. We have thus prepared several novel amphiphiles with two cationic headgroups and a single aliphatic chain. The amphiphiles have been synthesized via a three-step procedure beginning with a Williamson ether synthesis, followed subsequently by benzylic bromination, and a Menshutkin reaction. Synthetic details and aggregation studies of compounds with various counterions will be presented.