High sensitivity 1H-NMR spectroscopy of homeopathic remedies made in water

CHED 458

David Anick, david.anick@rcn.com, Harvard Medical School, McLean Hospital, 115 Mill St., Belmont, MA 02144
Homeopathic remedies made in water were studied via high sensitivity proton nuclear magnetic resonance spectroscopy. 57 remedy samples representing six starting materials and spanning potencies from 6C to 10M were tested along with 46 controls. By presaturating on the water peak, signals could be reliably detected that represented H-containing species at concentrations above 5 ìM. There were 35 positions where a discrete signal was seen in one or more of the 103 spectra, which should theoretically have been absent from the spectrum of pure water. Of these 35, fifteen were identified as machine-generated artifacts, eight were identified as trace levels of organic contaminants, and twelve were unexplained. Of the unexplained signals, six were seen in just one spectrum each. None of the artifacts or unexplained signals occurred more frequently in remedies than in controls, using a p<.05 cutoff. Some commercially prepared samples were found to contain traces of one or more of these small organic molecules: ethanol, acetate, formate, methanol, and acetone.