Development of a non-metal-based linchpin for bidirectional synthesis of all E-polyenes

CHED 297

Bruce H. Lipshutz, lipshutz@chem.ucsb.edu1, David B. Ball, dball@csuchico.edu2, Jillian E. Hostetter, dball@csuchico.edu2, and Claudia E. Avalos2. (1) Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106, (2) Department of Chemistry, California State University, Chico, Chico, CA 95929-0210
In our progress towards [12] and [14]-fecapentaene, our synthetic strategy has centered around the utilization of linchpin methodology. In this study a non-metal based linchpin is assembled and is used to bidirectionally elaborate the linchpinin to conjugated all E-polyenes.