INOR 830 |
| Vanadium dependent haloperoxidases are enzymes capable of oxidizing halides using hydrogen peroxide. Previously, the Pecoraro group developed a set of oxo-peroxo vanadium complexes as functional models for this enzyme class. Protonation of these compounds is essential for the reactivity and is supported by quantum chemical studies showing a decrease in the reaction barrier for oxidation of bromide and thioethers. Successful application of tBuOOH in this reaction could provide experimental evidence of where protonation takes place. The efficacy of tBuOOH for the epoxidation of propylene in the presence of d0 metal complexes is known. Here we report a study on the haloperoxidase and epoxidation activity of a series of tBuOO V(V) complexes.
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5th International Symposium on Chemistry and Biological Chemistry of Vanadium: Posters in Biochemistry and Chemistry
7:00 PM-10:00 PM, Tuesday, 12 September 2006 Moscone Center -- Hall D, Poster
Sci-Mix
Division of Inorganic Chemistry |
