POLY 68 |
| Since 1998 numerous examples of novel water-soluble diblock copolymers that exhibit so-called “schizophrenic” character have been reported.1-3 That is, the copolymer chains can self-assemble in aqueous solution in the absence of any cosolvent to form two distinct micelle structures. In each case, the individual blocks can be independently tuned to become either hydrophilic or hydrophobic by subtle adjustment of the solution temperature, solution pH or ionic strength. The original report in this new sub-field involved a tertiary amine methacrylate-based pH- and salt-responsive diblock copolymer.1 Later on, synthesis of various “schizophrenic” diblock copolymer having pH- and/or temperature-responsive characters were reported.2 Herein we report a novel “schizophrenic” ABC triblock copolymer [2-(diethylamino)ethyl methacrylate-b-2-(dimethylamino)ethyl methacrylate-b-2-(N-morpholino)ethyl methacrylate, PDEA-PDMA-PMEMA] which forms two different three-layer “onion” micelles [PDEA-core and PMEMA-core micelles, with solvated double blocks].3 We also successfully described the efficient synthesis of novel shell cross-linked micelles by cross-linking the inner shell of both micelles of this remarkable triblock copolymer. References (1) Bütün, V.; Billingham, N.C.; Armes, S.P., J. Am. Chem. Soc. 1998, 120, 11818. (2) Bütün, V.; Liu, S.; Weaver, J.V.M.; Bories-Azeau, X.; Cai, Y.; Armes, S.P., Reactive and Functional Polymers 2006, 66, 157. (3) Bütün, V.; Top, R.B.; Ufuklar, S., Macromolecules 2006, 39, 1216. |
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Multicompartment Micelles: Higher Order Self-assembly of Block Copolymers
1:30 PM-5:00 PM, Sunday, 10 September 2006 San Francisco Marriott -- Salon B2, Oral
Division of Polymer Chemistry |