Binding of copper(II) Schiff base complexes to DNA

INOR 136

Abdul K. Mohammed, mohammeda@wssu.edu and Lukmon B. Folarin. Department of Chemistry, Winston-Salem State University, 601 S. Martin Luther King, Jr., Drive, Wilveria B. Atkinson Science Bldg., Room 301, Winston-Salem, NC 27110
We have used literature procedures to synthesize and characterize two copper(II)-Schiff base complexes, with potential nuclease activities. The DNA binding properties have been studied by spectrophotometric titration. We plan to investigate their nuclease activities by studying their plasmid DNA cleaving abilities using agarose gel electrophoresis.
 

Bioinorganic Chemistry
7:00 PM-10:00 PM, Sunday, 10 September 2006 Moscone Center -- Hall D, Poster

Division of Inorganic Chemistry

The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006