Developments in flow-based fiber optic detection on a microfluidic format

CHED 181

Erika Garcia, erika.francine.garcia@gmail.com1, George M. Maltezos, maltezos@its.caltech.edu2, Axel Scherer2, Frank A. Gomez, fgomez2@calstatela.edu1, and Grady Hanrahan, ghanrah@calstatela.edu3. (1) Chemistry and Biochemistry, California State University, Los Angeles, 5151 State University Drive, Los Angeles, CA 90032, (2) Division of Engineering and Applied Science, California Institute of Technology, 1200 E. California Boulevard, Pasadena, CA 91125, (3) Department of Chemistry and Biochemistry, California State University, Los Angeles, 5151 State University Drive, Los Angeles, CA 90032
This poster describes the design and development of a flow-based fiber optic detection scheme on a microfluidic format. Central to this development is the placement of UV-Visible fiber optic cables in the fluid channel of a single two-layer poly(dimethylsiloxane) monolith. Pneumatically activated pumps and valves were incorporated into the microfluidic platform for continuous flow-based control and delivery of sample and reagents. Complete fabrication and precision alignment details are described along with the model analysis of reduced phosphorus species in natural waters via a novel colorimetric method.