INOR 631 |
| The spin state of iron in five coordinate ferric tetraphenylporphyrin, Fe(X)TPP, is affected directly by the field strength of the axial ligand. Previous studies have taken advantage of the highly sensitive 1H NMR β-pyrrole shifts to assign the relative spin state of iron and effectively rank weakly coordinating anions according to their corresponding field strength.1 Demonstrating the generality of this approach by using other nuclei is desirable. As such, compounds 1 and 2 have been synthesized to achieve this goal. The ferric metallated forms of both 1 and 2 have been probed using 13C and 19F NMR, respectively, scanning the exact range of weakly coordinating anions as in the previous parallel series. The synthesis of these complexes and a comparison of the ranking of field strengths along this set of ligands will be discussed with respect to the substantiation of this biologically significant analog to the Spectrochemical Series. 1 Reed, C. A. and Guiset, F. J. Am. Chem. Soc. 1996, 118, 3281; Evans, D. R. and Reed, C. A. J. Am. Chem. Soc. 2000, 122, 4660.
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Bioinorganic Chemistry
7:00 PM-10:00 PM, Tuesday, 12 September 2006 Moscone Center -- Hall D, Poster
Sci-Mix
Division of Inorganic Chemistry |
