Biomedical and pharmaceutical applications of "smart dust": Silicon-based photonic crystals

COLL 221

Michael J. Sailor, msailor@ucsd.edu, Department of Chemistry and Biochemistry, University of California, San Diego (UCSD), 9500 Gilman Drive, La Jolla, CA 92093-0332 and Ester Segal, essegal@ucsd.edu, Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0358.
The use of porous photonic materials made from nanostructured silicon in pharmaceutical, medical diagnostic, and microfluidic applications will be described. With a large free volume (50-90%) and an infinitely tunable nanostructure, these micron-sized "Smart Dust" particles have been found to be an excellent platform for the capture and controlled release of nanoparticles, small molecules, proteins, and enzymes. Impregnation of the particles with the various payloads can impart unique functions to the nanomaterials. For example, incorporation superparamagnetic nanoparticles provides a means to remotely manipulate, image and actuate the materials with an external electromagnetic field. Various in-vitro and in-vivo applications will be presented.
 

Advances in Nanomedicine
1:30 PM-5:20 PM, Monday, 11 September 2006 Sir Francis Drake -- Monterey/Cypress Rooms, Oral

Division of Colloid & Surface Chemistry

The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006