Biosensors based on biotin-linked viologen SAM's on gold in AAO pores

COLL 318

Robert D. Long, robert.long@enmu.edu1, Juchao Yan, juchao.yan@enmu.edu2, Prashant M. V. Muttanapalli1, and Emmanuel Amoah1. (1) Physical Sciences, Eastern New Mexico University, Station # 33 Roosevelt Hall, Portales, NM 88130, (2) Department of Physical Sciences, Eastern New Mexico University, 1500 S Ave K, Portales, NM 88130
Alkanethiol linked viologens are assembled on a gold monolayer surface with subsequent solid-phase modification to add linker molecules and receptors (via an amide bond) for purposes of creating arrays of biosensors in AAO membrane pores. In the initial work, biotin is conjugated to the viologens which will be tested as redox sensors for avidin binding via a gold electrode. The use of solid-phase synthesis on the viologen SAM's reduces problems in purification that would be necessitated in solution-phase synthesis.

 

Chemistry at Membrane Interfaces
6:00 PM-8:00 PM, Monday, 11 September 2006 Moscone Center -- Room 104, Poster

Division of Colloid & Surface Chemistry

The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006