Electrochemical detection of catechol neurotransmitter in the presence of ascorbic acid at conducting poly 2,2-bithiophene platinum electrode

ANYL 113

Suzanne K. Lunsford, suzanne.lunsford@wright.edu, Department of Chemistry, Wright State University, 3640 Colonel Glenn Hwy, Dayton, OH 45435
The overriding goal has been to develop more advanced techniques to detect common neurotransmitters in the presence of common interferents. Biological and neurological compounds, such as catechol, are of interest to neuroscientists. Catechol is secreted in the brain and altered levels have been associated with mental and such behavioral disorders as schizophrenia, attention deficient disorder, Alzheimer's disease, Parkinson's disease, eating disorders, epilepsy, amphetamine and cocaine addiction . The presence of common interferents such as ascorbic acid, may complicate catechol analysis. This experiment uses cyclic voltammetry to detect catechol in the presence of common interferents. Electrodes modified by the electrodeposition of the conducting poly (2, 2-bithiophene) film (PBTP) electrode were studied as a chemical sensor for catechol and biological molecules of industrial and medicinal interest. The scope of optimizing the electrode to detect catechol in the presence of ascorbic acid by utilizing cyclic voltammetry will be discussed with Scanning Electron Microscopy data.

 

General Papers
7:00 PM-9:00 PM, Sunday, 10 September 2006 Moscone Center -- Hall D, Poster

Division of Analytical Chemistry

The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006