Use of smart holograms as diagnostic tools

ANYL 329

Adrian Horgan, adrian.horgan@smartholograms.com, Alex Marshall, Satyamoorthy Kabilan, Chris Creasey, Kathryn Dean, Simon Kew, Stephen Terrell, Wendy McLean, Christian Johnson, Louise Affleck, Ruth Dunleavey, and Heike Sandler. Smart Holograms Ltd, 291 Cambridge Science Park, Milton Road, Cambridge, United Kingdom
The need for simple, robust and inexpensive analytical devices within the environmental, security, food and biomedical industries is well established. However, concerns over the cost, manufacturability and durability of biosensor technologies has limited their impact. These issues are being addressed through the development of novel sensing systems, one example of which is the use of 'smart' holograms. 'Smart' holograms utilise the principles of volume holography with a Denisyuk holographic grating recorded within a 'smart' polymer. Unlike conventional holographic recording media, the 'smart' polymers contain receptors that allow the holograms to act as transducers. Interaction with a specific analyte or stimulus changes the colour, image or brightness of the hologram and these changes can be easily visualised and quantified (figure below). A series of products are currently under development and this talk will present the latest results applying to glucose monitoring and chemical and biological threat detection.