MEDI 276 |
| The estrogen receptor-related receptors (ERRs) are a subfamily of three nuclear receptors (NRs) which are most closely related to the classical estrogen receptors (ERs). Although they were among the first orphan NRs to be identified, many of the physiological roles and potential therapeutic applications of the ERRs await further elucidation. Herein we describe the identification and application of ERRα and ERRγ chemical tools in the investigation of the receptors as targets for drug discovery. |
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Reverse Pharmacology: The Role of Medicinal Chemistry in Novel Target Identification
1:30 PM-4:50 PM, Monday, 11 September 2006 Moscone Center -- Room 102, Oral
Division of Medicinal Chemistry |