Formation of a multi-channel colorimetric polymer as a sensor for biogenic amines

POLY 257

Clifton J. Stephenson, stephenson@mail.chem.sc.edu, Department of Chemistry & Biochemistry, University of South Carolina, 631 Sumter St., Columbia, SC 29208 and Ken D. Shimizu, Department of Chemistry and Biochemistry, University of South Carolina, 631 Sumter Street, Columbia, SC 29208.
The use of multiple dyes in a single sensor can create a highly sensitive multidimensional sensor system. Incorporation of a multiple dye system into a polymer can yield a multi-signal output within a single polymer. Tethering the dyes into a polymer increases solvent options by removing dye solubility as a variable in set up and testing, enhances the sensitivity of the system by amplifying dye concentration, and affords compatibility with automated testing methodologies. To form colorimetric polymers sensors, the incorporated dyes should exhibit an on/off or off/on response in the presence of the analyte. Dyes were formed into monomers and then incorporated into the polymer as comonomers and demonstrated the ability to discriminate closely related amines. Presented, will be our current progress towards the incorporation of multiple xanthene dyes into a polymer to yield a polymer for the detection of biogenic small amines.
 

Polymers in Biosensors and Biochips
8:30 AM-11:50 AM, Monday, 11 September 2006 San Francisco Marriott -- Salon 12/13, Oral

Division of Polymer Chemistry

The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006