Fabrication of tunable diffraction gratings based on thermoresponsive NIPAAm hydrogels for grating coupled surface plasmon resonance

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Beinn V. O. Muir, beinnmuir@stanford.edu1, Cathrin Corten2, Dirk Kuckling, dirk.kuckling@chemie.tu-dresden.de2, Amal Kasry3, Wolfgang Knoll, knoll@mpip-mainz.mpg.de3, and Curtis W. Frank, curt.frank@stanford.edu1. (1) Department of Chemical Engineering, Stanford University, 381 North-South Mall, Stanford, CA 94305, (2) Fachrichtung für Chemie und Lebensmittelchemie, TU Dresden, D-01062 Dresden, Germany, (3) Materials Science, Max Planck Institute for Polymer Research, Ackermannweg 10, Mainz, Germany
Classical surface plasmon resonance (SPR) studies are normally carried out using either the Kretschmann configuration, where coupling is directed through a prism, or with a grating coupled configuration. Grating coupled SPR offers many advantages over the Kretschmann configuration, but has not had widespread use due to the fixed nature of the grating structure. A variable diffraction grating SPR configuration, as described here, allows for dynamic tuning of the grating properties. Theoretical simulations have been carried out investigating the angular response as a function of grating parameters for long wavelength gratings. Here we report the use of temperature sensitive N-isopropylacrylamide co-polymers as active components of a variable diffraction grating support for grating coupled surface plasmon analysis. The device fabrication methodology and device configuration is described in detail, and potential applications in biosensing are discussed.
 

Polymers in Biosensors and Biochips
8:30 AM-11:50 AM, Monday, 11 September 2006 San Francisco Marriott -- Salon 12/13, Oral

Division of Polymer Chemistry

The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006