ANYL 221 |
| Characterization of the physical form of solid drug substances or drug product is a critical issue in pharmaceutical development. Solid-state nuclear magnetic resonance (SSNMR) can readily distinguish and differentiate between polymorph and pseudo-polymorph forms of many pharmaceutical compounds. This session will present the application of routine solid-state NMR spectroscopy towards characterization during both API and formulation process development. Topics include: (1)Polymorph form identification and quantitation, (2)solvate identification and characterization, (3)multiple solid phase detection through relaxation methods, (4)characterizing complex polymorph systems, and (5)detection and quantitation of amorphous formation during processing. |
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Characterization of Polymorphic Compounds and Mixtures
8:30 AM-11:55 AM, Tuesday, 12 September 2006 Moscone Center -- Room 130, Oral
Division of Analytical Chemistry |