ANYL 255 |
| Cells must receive and process information (growth factors, hormones, cytokines) arriving at their plasma membrane. To formulate a response to these stimuli, cells possess complex signaling circuitry. However, much remains unknown about these signal processing pathways. A key reason is the lack of high-throughput technologies to assess the state of these pathways at the level of a single cell. Array-based strategies for cells adherent to a surface and microfluidic methods for nonadherent cells have the potential to fulfill these needs. The lab is currently developing microanalytical platforms to array, address and analyze single, adherent cells. Microfabricated systems for selection, interrogation, and lysis of a single cell followed by electrophoretic separation of the cell's contents are also under development. Recent results on assay development in these devices will be presented.
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Interfacing Biology with Lab-On-A-Chip Separations
8:30 AM-11:55 AM, Wednesday, 13 September 2006 Moscone Center -- Room 130, Oral
Division of Analytical Chemistry |