Absolute configuration of proanthocyanidins via circular dichroism

CELL 77

Daneel Ferreira, dferreir@olemiss.edu, Department of Pharmacognosy, The University of Mississippi, University, MS 38677, Xing-Cong Li, xli7@olemiss.edu, National Center for Natural Products, The University of Mississippi, University, MS 38677, and Jannie P. J. Marais, National Center for Natural Products Research, The University of Mississippi, University, MS 38677.
Circular dichroism (CD) is a powerful in the study of the absolute configuration of organic molecules. This is especially prevalent in the case of the proanthocyanidins, which are more often than not, non-crystalline, hence excluding X-ray crystallographic studies as a means to assess absolute configuration. The unique array of chromophores in this complex group of naturally occurring polyphenolic biomolecules facilitates definition of their absolute configuration via chiroptical studies. We will review current knowledge and also allude to future trends steering research in this area of research.
 

Fifth Tannins Conference
1:00 PM-4:00 PM, Monday, 11 September 2006 Palace -- Sea Cliff Room, Oral

Division of Cellulose & Renewable Materials

The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006