Synthesis of organic epoxides using a spinning tube-in-tube reactor

I&EC 120

James T. Ciszewski, Ciszewski.Jim@epamail.epa.gov and Michael A. Gonzalez, gonzalez.michael@epa.gov. Sustainable Technology Division, United States Environmental Protection Agency, 26 West Martin Luther King Drive, Cincinnati, OH 45268
The U. S. Environmental Protection Agency (USEPA) and Kreido Laboratories have established a Cooperative Research and Development Agreement (CRADA) collaboration, to develop and commercialize green and sustainable chemistries in the area of industrial chemical synthesis. The STT™ reactor utilizes process intensification techniques to increase the rate, yield, and selectivity of chemical reactions used in producing commercially important materials. A wide variety of organic epoxides were synthesized in moderate to high yields in a spinning tube-in-tube reactor (STT®, Kreido Laboratories, Camarillo California). A systematic evaluation of oxidant and substrate reactivities will be presented.