ORGN 624 |
| Fluorous technology employs a fluorous “phase tag” to facilitate reaction mixture purifications. Due to its inert nature, the tag has limited impact on the chemical property of the molecule. The separation power comes from the interaction between the fluorous molecule and the fluorous solvent or sorbent. The homogeneous solution-phase reactions and easy “phase tag” separations provide advantages in organic synthesis, especially for parallel and high-throughput synthesis. This presentation describes our recent effort in the development of new fluorous reagents (scavengers, catalysts, protecting groups) and separation techniques such as plate-to-plate solid-phase extraction. The combination of fluorous chemistry with microwave reactions, multicomponent reactions, and diversity-oriented synthesis for making compound libraries will also be described. |
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Technical Achievements in Organic Chemistry Awards
8:15 AM-12:00 PM, Wednesday, 13 September 2006 Moscone Center -- Room 135, Oral
Division of Organic Chemistry |