PMSE 280 |
| New biodegradable poly(ester urethane) polymers (PEURs) consisting of nontoxic building blocks have been synthesized by active polycondensation. Variation of the three constituent building blocks: alpha-amino acids, aliphatic diols and di-p-nitrophenyl carbonate resulted in polymers covering a wide range of thermal and mechanic properties. The effects of the structure of these building block components on physico-chemical properties of the polymers have been examined.: e.g. incorporation of 1,4: 3,6-dianhydro-D-glucitol increases Tg and decreases elasticity. In vitro cell culture tests showed excellent biocompatibility of PEURs. The wide range of thermal and mechanic properties of PEUR polymers makes them an excellent choice for different drug delivery applications. |
|
Joint PMSE/POLY Poster Session
6:00 PM-8:00 PM, Tuesday, 12 September 2006 Moscone Center -- Hall D, Poster
Division of Polymeric Materials: Science & Engineering |