Recoverable polymer hydrogels based on covalently complex by new cytocompatible phospholipid polymers

POLY 429

Tomohiro Konno, konno@mpc.t.u-tokyo.ac.jp, Department of Materials Engineering, and Center for NanoBio Integration, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan and Kazuhiko Ishihara, ishihara@mpc.t.u-tokyo.ac.jp, Department of Materials Engineering, Bioengineering, and Center for NanoBio Integration, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan.
In this study, we prepared the polymeric hydrogel formed by shaking of two kinds of polymer aqueous solutions. We designed a new phospholipid polymer containing p-phenylboronic acid moiety, that is, poly[2-methacryloyloxyethyl phosphorylcholine (MPC) -co-n-butyl methacrylate (BMA) -co-p-vinylphenylboronic acid (VPBA)](PMBV). We report the synthesis and characterizations of new MPC polymer, formation and properties of hydrogel with polyol compound such as poly(vinyl alcohol), and behavior of fibroblast cells on/in the hydrogel. The new hydrogel system formed by two kinds of polymer aqueous solution was applied as cell-container.
 

7th International Biorelated Polymers Symposium
6:00 PM-8:00 PM, Tuesday, 12 September 2006 Moscone Center -- Hall D, Poster

Division of Polymer Chemistry

The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006