Engineered protein polymers

POLY 582

Hongkwan Cho, Kunal A. Shah, and Jin K. Montclare, jmontcla@poly.edu. Department of Chemical and Biological Sciences, Polytechnic University, 6 Metrotech Center, Brooklyn, NY 10019
Traditional methods for polymer synthesis rely on conventional polymerization chemistries that lead to products that are polydisperse. Nature, on the other hand, has been able to generate biopolymers in the form of proteins with varied monomer units that are highly sequence specific and monodisperse. Here we offer an alternative to synthetic polymer synthesis by exploiting nature's biosynthetic mechanisms to generate protein polymers that may serve as biodegradable materials. We have designed genetically engineered artificial protein co-polymers based on natural extracellular matrix proteins: elastin and cartilage oligomeric matrix protein. We will discuss the synthesis and characterization of the various engineered co-polymers.
 

Biocatalysis in Polymer Science
8:30 AM-11:45 AM, Wednesday, 13 September 2006 San Francisco Marriott -- Salon 12/13, Oral

Division of Polymer Chemistry

The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006