AGRO 6 |
| α-Chloralose is an anesthetizing chemical used to aid in the capture of nuisance birds. It causes central nervous system depression, which makes the affected birds easier to capture and minimizes injury to the birds during capture. To prevent possible human ingestion of α-chloralose, there is a 30 day moratorium on α-chloralose use with respect to hunting season. This moratorium limits the usefulness of this wildlife management technique. To generate pharmacokinetic data which could possibly lead to reducing the length of this moratorium, we conducted an experiment to identify the absorption and excretion of α-chloralose. Mallard ducks were given a single dose of 14C labeled α-chloralose. Expired air and excreted feces were collected and analyzed for 14C content. Once excretion levels returned to near-background levels, the birds were euthanized and their organs were removed and analyzed for 14C content. Results indicated that α-chloralose is rapidly excreted from the birds with approximately 80% of the radioactivity excreted in the first 24 hours and total excretion levels returning to near-background within 3 days of dosing. |
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Agrochemical Residue & Metabolism Chemistry
8:30 AM-11:30 AM, Sunday, 10 September 2006 San Francisco Marriott -- Salon 1, Oral
Division of Agrochemicals |