POLY 556 |
| ABSTRACT: The complex formation of oppositely charged surfactants with some polypeptides are known to induce b-sheet or helix formation. Here we report on the complex formation of cylindrical brush polymers with poly-L-lysine side chains and sodium dodecylsulfate (SDS). With increasing amount of added surfactant the cylindrical polymers first adopt a helical conformation with a pitch of approximately 15-20 nm followed by a spherically collapsed structure before eventually precipitation occurs. CD measurements suggest that the helix formation of the cylindrical brush polymers is driven by the hydrophobicity of the b-sheets formed by the PLL side chain-SDS complexes. |
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7th International Biorelated Polymers Symposium
8:30 AM-12:40 PM, Wednesday, 13 September 2006 San Francisco Marriott -- Salon 14/15, Oral
Division of Polymer Chemistry |