Enzymatic polymerization in supercritical carbon dioxide

POLY 392

Silvia Villarroya, silvia.lidon@nottingham.ac.uk, School of Chemistry, The University of Nottingham, University Park, Nottingham, NG7 2RD, United Kingdom
Herein, we report the investigations carried out on the use of an environmentally friendly reaction media like supercritical CO2 for enzymatic synthesis of functional materials. The expected enzyme performance enhancement in these media has been proven. The retention of the enzyme activity in scCO2 has been also demonstrated. In previous work, we initially reported the enzyme-catalyzed ring opening polymerization (eROP) of caprolactone (CL) in supercritical carbon dioxide (scCO2). Enzymatic ring-opening polymerisation (eROP) of caprolactone (CL) and atom transfer radical polymerisation (ATRP) of methyl methacrylate (MMA) were integrated into a one step chemoenzymatic route to yield poly(CL-block-MMA) (PCL-b-PMMA) in scCO2. We extend the scCO2 methodology to the synthesis of novel diblock copolymers consisting of a semifluorinated block of poly(1H,1H,2H,2H-perfluorooctyl methacrylate) and a hydrocarbon block of polycaprolactone (PFOMA-b-PCL) by the combination of e-ROP and ATRP in a two step approach.

Biocatalysis in Polymer Science
1:30 PM-4:45 PM, Tuesday, 12 September 2006 San Francisco Marriott -- Salon 12/13, Oral

Division of Polymer Chemistry

The 232nd ACS National Meeting, San Francisco, CA, September 10-14, 2006