Nanostructure applications: Tutorial

POLY 5

Anjan Nan, anan@rx.umaryland.edu, Pharmaceutical Sciences, Center for Nanomedicine and Cellular Delivery, University of Maryland, Baltimore, 20 Penn Street, Room 622 (HSFII), Baltimore, MD 21201 and Hamid Ghandehari, hghandeh@rx.umaryland.edu, Department of Pharmaceutical Sciences, Center for Nanomedicine and Cellular Delivery, University of Maryland, Baltimore, School of Pharmacy, 20 Penn Street-Room 625, Baltimore, MD 21201-1180.
Recent advances in nanotechnology have made available structures with controlled properties in the nanometer size range. Nanomaterials are similar in size to many functional biomolecules which makes them biologically useful. By controlling structure at the nanoscale, one can tailor properties to better suit integration with biological systems. Nanoscale structures have found applications in a wide range of areas including research enablers, biosensing, imaging and targeted drug delivery. The focus of this tutorial will be on recent advances in the design and development of novel nanostructures for biomedical applications. Emphasis will be placed in the area of targeted delivery of bioactive and imaging agents. Examples of nanoconstructs to be discussed include gold nanoparticles, magnetic nanotubes, dendrimers and polymer therapeutics.